Powered Research, LLC is a preclinical CRO specializing in ophthalmic models. Our team led by Dr. David Culp and Dr. Brian Gilger has proven expertise in:
Ophthalmic Examinations
- Slit lamp biomicroscopy with photography
- Ocular fundus photography
- Hackett-McDonald microscopic irritation scores
- Tonometry (intraocular pressure measurement)
- Anterior and posterior segment optical coherence tomography
- High frequency ultrasound (ultrasound biomicroscope)
- Other examination techniques
Models of Disease
- Induced acute & chronic uveitis (rat / rabbit)
- Cataract surgery (rabbit)
- Corneal ulcer / keratitis (alkali or scrape models)
- Allergic conjunctivitis (guinea pig)
- VEGF-induced neovascularization
Biocompatibility / Toxicity / PK studies
- Intravitreal implants – drug delivery, other
- Intracameral implants – drug delivery, other
- Glaucoma filtering devices